We're Here to Help

239.489.0024

Contact Us

info@airscience.com

PCR Workstation vs. Biosafety Cabinet: Understanding the Differences

Selecting the appropriate equipment is crucial in laboratory environments where contamination control is paramount. When determining the most appropriate equipment for your contamination-sensitive application, it’s important to consider the purpose as well as the protection level. When it comes to PCR Workstations and Class II, Type A2 biosafety cabinets, or biological safety cabinets (BSCs), understanding the differences is key.

Purpose and Applications
PCR Workstations:
  • Primary Function: Designed to protect samples from contamination during Polymerase Chain Reaction (PCR) processes.
  • Ideal for molecular biology tasks, such as DNA amplification, where sample integrity is critical.
  • Not suitable for handling infectious agents or hazardous materials.
Biosafety Cabinets:
  • Primary Function: Engineered to protect the user, the environment, and the work surface from exposure to biohazards and cross-contamination.
  • Essential for microbiological work involving pathogens, cell cultures, and other biohazardous materials.
  • Required in laboratories working with Biosafety Level 1-3 agents.
Protection Levels
PCR Workstations:
  • Protection Level: Safeguards samples from particulates and contaminants.
  • User Protection: Does not provide protection for the user or the environment.
Biosafety Cabinets:
  • Protection Level: Offers comprehensive protection from hazardous and nonhazardous materials.
  • User Protection: Provides protection for samples, users, and the environment.
Airflow and Filtration
PCR Workstations:
  • Airflow: Utilizes vertical laminar airflow to maintain a sterile environment over the work surface.
  • Filtration: Equipped with HEPA filters to remove particulates from the air.
  • UV Sterilization: Often includes UV lamps for decontamination between processes.
Biosafety Cabinets:
  • Airflow: Incorporates a combination of inflow and downflow air patterns to prevent escape of contaminants.
  • Filtration: Features HEPA filters for both incoming and outgoing air, ensuring containment.
  • UV Sterilization: May include UV lamps, but primary protection is through airflow design and filtration.

Air Science's Solutions

Selecting between a PCR workstation and a biosafety cabinet depends on your laboratory’s specific needs. For tasks focused on preventing sample contamination without exposure to hazardous materials, a PCR workstation like the Air Science Purair® PCR Workstation is more appropriate.

Purair PCR Workstations offer protection by laminar flow for PCR amplification handling that is extremely sensitive to contamination. Decontamination between applications is simplified via a germicidal UV lamp, which creates light emission conditions known to provide safe decontamination.

However, if your work involves biohazardous agents, a biosafety cabinet such as the Purair® BIO is essential for comprehensive protection. The Class II, Type A2 Purair BIO provides a primary containment work area for life science research, cell culture processing, and other applications where protection of the user, the work product, and the environment, and mitigation of cross-contamination on the work surface are needed.

Ready to Enhance Your Laboratory's Safety and Efficiency?

Explore Air Science’s range of PCR workstations and biosafety cabinets to find the perfect fit for your laboratory needs. Visit ductless.com to browse and purchase products online.

Post Comment

Your email address will not be published. Required fields are marked *